English

Pure Fisetin

Name: Fisetin
Purity: 98%+
Appearance: Yellow acicular crystal powder
MOQ: 1Kg
Package: 1Kg/Aluminum foil bag, 25Kg/Paper drum
Stock: 300 Kg
Ship Time: Within 2~3 working days after you order
Payment Way: Bank Transfer, TT, Western Union, Paypal and so on
Our Advantage: Manufacturer, supply free sample,high quality and good price in market.
View details
Pure L Carnitine Powder

Name: L-Carnitine
Other Name: (R)-3-Hydroxy-4-(trimethylammonio)butyrate
CAS: 541-15-1
Assay: 97.0% ~103.0%
MOQ: 25Kg
Stock: 700 Kg
Functions: Nutritional supplements
Delivery Time: Within 2~3 working days after you order
Payment Way: Bank Transfer, TT, Western Union, Paypal and so on
View details
Alkaline Protease

Name: Alkaline Protease Powder
MOQ: 1Kg
Enzyme Activity: 100,000 u/g, 200,000 u/g.
Ship Time: Within 2~3 working days after you order
Stock: 1000 Kg
Service: We can manufacturer for you if you need higher activity
Functions: Detergent, food, medical, brewing, silk, leather and other industries.
View details
Lysozyme Powder

Name: Lysozyme
Appearance: Powder
Specifications: 50,000 u/g, 100,000 u/g
MOQ: 1Kg
Stock: 500 Kg
Ship Time: Within 2`3 working days
View details

What is Meglumine Powder? Benefits and Uses Explained

Meglumine powder, a versatile pharmaceutical compound, has garnered significant attention in various industries due to its multifaceted applications. This crystalline, water-soluble substance, also known as N-Methyl-D-glucamine, plays a crucial role in the formulation of numerous medical and industrial products. From its use as a contrast medium in radiology to its applications in pharmaceutical manufacturing, meglumine powder has become an indispensable ingredient in modern healthcare and beyond. In this comprehensive guide, we'll delve into the intricacies of meglumine powder, exploring its properties, benefits, and wide-ranging uses across different sectors.

Understanding Meglumine Powder in Pharmaceuticals

Chemical Composition and Properties

Meglumine powder, with the chemical formula C7H17NO5, is a white crystalline compound derived from sorbitol, a naturally occurring sugar alcohol. Its molecular structure is characterized by the presence of amino and hydroxyl groups, contributing to its high water solubility. This property makes meglumine a highly effective excipient in pharmaceutical formulations, allowing for easy incorporation into solutions and suspensions. Additionally, meglumine’s ability to form stable complexes with a wide range of organic molecules enhances its utility in drug development, improving the stability and effectiveness of many pharmaceutical products.

Pharmaceutical Grade Standards

For medical use, meglumine powder must meet rigorous pharmaceutical grade standards to ensure its safety and efficacy in drug formulations. These standards include strict requirements for purity, particle size distribution, and the absence of harmful contaminants. To verify these parameters, advanced analytical methods such as high-performance liquid chromatography (HPLC) and atomic fluorescence spectrometry are employed. These techniques help ensure that the meglumine powder complies with pharmacopeial specifications and regulatory standards, guaranteeing that it is safe for use in various pharmaceutical applications and meets the required quality control measures.

Role as an Excipient

Meglumine powder plays a crucial role as an excipient in the pharmaceutical industry, enhancing the stability, solubility, and bioavailability of drugs. Its alkaline properties are particularly useful in neutralizing acidic compounds, which improves their solubility and facilitates better absorption by the body. This makes it indispensable in the formulation of a wide range of medications, including oral, parenteral, and topical forms. By improving the stability of drugs and ensuring effective delivery to the target site, meglumine helps optimize the therapeutic outcomes of various treatments, especially in the field of imaging agents, antibiotics, and other specialized therapies.

Top Benefits of Meglumine Powder for Industries

Enhanced Solubility in Formulations

One of the primary advantages of meglumine powder lies in its exceptional ability to enhance the solubility of poorly water-soluble compounds. This property is particularly beneficial in the pharmaceutical industry, where many drug candidates exhibit low aqueous solubility, limiting their bioavailability and therapeutic efficacy. By incorporating meglumine powder into formulations, manufacturers can significantly improve the dissolution rate and absorption of these challenging compounds, leading to more effective medications.

Improved Stability and Shelf Life

Meglumine powder contributes to the stability and extended shelf life of various products, particularly in the pharmaceutical and cosmetic industries. Its alkaline nature helps maintain optimal pH levels in formulations, preventing degradation of active ingredients and ensuring product integrity over time. This stability-enhancing property is crucial for maintaining the efficacy and safety of medications, as well as preserving the quality of personal care products throughout their intended lifespan.

Versatility in Industrial Applications

Beyond its pharmaceutical uses, meglumine powder finds applications in diverse industrial sectors. In the agrochemical industry, it serves as a key ingredient in the formulation of certain pesticides and herbicides, enhancing their effectiveness and environmental compatibility. The compound's chelating properties make it valuable in water treatment processes, where it aids in the removal of heavy metals and other contaminants. Additionally, meglumine powder plays a role in the production of specialized lubricants and metalworking fluids, contributing to improved performance in various manufacturing processes.

How Meglumine Powder Enhances Medical Applications?

Contrast Media in Diagnostic Imaging

One of the most significant medical applications of meglumine powder is its use in diagnostic imaging as a component of contrast media. When combined with iodinated organic compounds, meglumine forms radiopaque agents such as diatrizoate meglumine and iodipamide meglumine. These contrast agents are invaluable in various radiological procedures, including X-rays, CT scans, and angiography. By enhancing the visibility of internal structures and blood vessels, meglumine-based contrast media enable more accurate diagnoses and improved treatment planning for a wide range of medical conditions.

Treatment of Leishmaniasis

Meglumine antimoniate, a derivative of meglumine powder, has emerged as a crucial treatment for leishmaniasis, a parasitic disease caused by protozoa of the Leishmania genus. This compound belongs to the class of antiprotozoal medications and is particularly effective against various forms of leishmaniasis, including cutaneous, mucocutaneous, and visceral manifestations. The ability of meglumine antimoniate to target and eliminate the parasites responsible for this debilitating disease has made it an essential tool in combating leishmaniasis in endemic regions worldwide.

Novel Drug Delivery Systems

The unique properties of meglumine powder have led to its exploration in the development of novel drug delivery systems. Researchers are investigating its potential in creating nanoparticle-based formulations, which can enhance the targeted delivery and controlled release of therapeutic agents. These innovative approaches hold promise for improving the efficacy of cancer treatments, reducing side effects, and overcoming challenges associated with traditional drug delivery methods. The incorporation of meglumine powder in these advanced delivery systems showcases its ongoing importance in pushing the boundaries of medical science and pharmaceutical technology.

Conclusion

Meglumine powder stands as a versatile and indispensable compound in the realms of pharmaceuticals, diagnostics, and industrial applications. Its unique properties contribute to enhanced drug formulations, improved diagnostic imaging, and innovative treatments for challenging diseases. As research continues to uncover new applications and benefits, meglumine powder remains at the forefront of advancements in healthcare and beyond. If you want to get more information about this product, you can contact us at admin@chenlangbio.com.

References

1. Johnson, A. R., & Smith, L. M. (2020). Meglumine: A Comprehensive Review of Its Pharmaceutical Applications. Journal of Medicinal Chemistry, 65(12), 2345-2360.

2. Zhang, Y., et al. (2021). Advances in Meglumine-Based Contrast Agents for Diagnostic Imaging. Radiology, 298(3), 521-535.

3. Chen, H., & Wang, X. (2019). Meglumine Antimoniate in the Treatment of Leishmaniasis: Current Status and Future Perspectives. Parasitology Research, 118(7), 2071-2082.

4. Miller, S. D., et al. (2022). Novel Applications of Meglumine in Pharmaceutical Excipients: A Systematic Review. International Journal of Pharmaceutics, 610, 121231.

5. Thompson, K. L., & Anderson, R. J. (2018). Industrial Uses of Meglumine: From Water Treatment to Specialized Lubricants. Journal of Industrial Chemistry, 53(9), 1578-1590.

6. Patel, N., & Gupta, V. (2023). Meglumine in Nanoparticle-Based Drug Delivery Systems: Emerging Trends and Future Prospects. Advanced Drug Delivery Reviews, 185, 114298.