Rotundine Powder

Tetrahydropalmatine (THP) rotundine powder is an isoquinoline alkaloid found in several different plant species, mainly in the genus Corydalis (Yan Hu Suo), but also in other plants such as Stephania rotunda.

It is an antagonist of dopamine D1, D2 and D3 receptors with IC 50 s of 166 nM, 1.4 μM and 3.3 μM, respectively. Rotundine is also an antagonist of 5-HT 1A with an IC 50 of 370 nM.

Rotundine have analgesia and Sedative Hypnotic activity, can depress the chtonic persistent pain and splanchna dull pain. It has effect of promoting blood circulation to remove blood stasis and promoting circulation of qi to relieve pain.

It is an antipyretic and analgesic drug. It is mainly used in clinical treatment of pain of gastric ulcer and duodenal ulcer, menstrual pain, prevent contraction pain after childbirth, tension insomnia, spasmodic cough, etc.

Basic Information:

Function of Tetrahydropalmatine Powder:

1. Tetrahydropalmatine has the protective effect on liver injury induced by carbon tetrachloride in mice.

2. Rotundine powder tetrahydropalmatine has analgesia and sedative-hypnotic activity, can depress the chtonic persistent pain and splanchna dull pain.

3. It has effect of promoting blood circulation to remove blood stasis and promoting

circulation of qi to relieve pain.

4. It is often used for hypochondriac pain due to stagnation of the liver-qi,

stomachache due to stagnation of the stomach-qi, hernial pain.

Applicaction of Tetrahydropalmatine Rotundine Powder:

1.Pharmaceutical chemical raw materials and dietary supplement ingredients;

2.Pesticides and plant growth regulator materials,