Where to Buy Hexamidine Diisethionate in Bulk
2025-11-05 15:54:55
Where to Buy Hexamidine Diisethionate in Bulk-CHEN LANG BIO TECH Global Supplier for Cosmetic Formulations
Hexamidine diisethionate has quickly become a leading antimicrobial ingredient for cosmetic preservation and scalp-care innovation. As international beauty brands shift toward cleaner, safer, and more effective preservation systems, demand for bulk Hexamidine Diisethionate continues to rise worldwide.
At CHEN LANG BIO TECH, we serve as a China hexamidine diisethionate manufacturer with full production capability, ISO and BRC certification, and over a decade of experience in supplying cosmetic-grade actives. Our facility specializes in high-purity crystalline hexamidine isethionate that meets the stringent microbiological and regulatory requirements of global formulators.
Whether you are developing a skin-care serum, scalp-care lotion, or hexamidine diisethionate shampoo, understanding what this ingredient does—and where to buy it in reliable bulk supply—is essential for product quality and compliance.
What Is It?
Chemically, it is a cationic diamidine compound supplied as a di-isethionate salt. This configuration provides excellent water solubility and chemical stability, making it compatible with both rinse-off and leave-on systems.
The ingredient functions as a broad-spectrum antimicrobial that controls bacteria, yeast, and mold while remaining gentle on the skin. Its positive charge allows it to interact with microbial membranes, disrupting cell integrity without aggressive chemical reactions.
Compared with traditional preservatives such as parabens or isothiazolinones, hexamidine diisethionate delivers reliable protection at low concentrations (typically 0.05–0.10 %), without affecting the color, viscosity, or fragrance of a formulation.
Why Global Brands Choose Hexamidine Diisethionate Powder
High Purity and Performance-Our hexamidine diisethionate powder is produced under pharmaceutical-grade conditions, with purity levels exceeding 99%. Each batch is tested for heavy metals, residual solvents, and microbial contamination.
Broad Formulation Compatibility-It integrates seamlessly into emulsions, serums, gels, and surfactant-based systems. The di-isethionate salt ensures superior solubility even in cold-process formulations.
Mild and Non-Sensitizing-Extensive safety assessments confirm that hexamidine diisethionate causes minimal irritation, making it suitable for sensitive-skin and baby-care products.
Dual Functionality-Besides preserving formulations, it supports skin-balance and scalp health. In Hexamidine Diisethionate shampoo, the ingredient helps reduce microbial overgrowth linked to dandruff and scalp irritation.
Regulatory Confidence-Approved by global authorities including the EU SCCS and the U.S. CIR Expert Panel for use up to 0.10 % concentration.
These properties make Hexamidine Diisethionate a cornerstone in modern cosmetic formulation—especially for brands prioritizing efficacy, safety, and transparency.
Applications Across Cosmetic and Personal-Care Formulations
1. Skin Care and Dermatological Formulations
In facial serums, moisturizers, and toners, it prevents microbial growth while gently purifying the skin surface. When combined with niacinamide, zinc PCA, or botanical actives, it provides oil-control and skin-clarifying effects without the dryness associated with alcohol-based antimicrobials.
2. Scalp and Hair Care Products
Hexamidine Diisethionate shampoo formulations have shown excellent results in controlling dandruff and scalp irritation. The ingredient targets Malassezia furfur and Cutibacterium acnes, restoring scalp microbiome balance. Its mildness makes it an ideal replacement for harsher anti-dandruff agents like zinc pyrithione.
3. Deodorants and Body Care
Its antibacterial efficacy extends to deodorant sprays, feminine hygiene products, and cleansing foams. The absence of parabens or formaldehyde donors allows brands to market these products as clean-label and hypoallergenic.
4. Cosmetic Preservative Systems
Hexamidine Diisethionate acts as the core of modern preservative blends, often paired with phenoxyethanol, caprylyl glycol, or ethylhexylglycerin for synergistic protection. This approach reduces the total preservative load while maintaining strong microbial control—aligning perfectly with global clean-beauty trends.
Formulation and Processing Guidelines
As a technical manufacturer, CHEN LANG BIO TECH provides detailed formulation guidance to ensure optimal performance of bulk Hexamidine Diisethionate in different product types.
Usage Level: 0.05–0.10 % depending on contamination risk and product type.
Incorporation: Add to the aqueous phase below 80 °C to preserve stability.
pH Range: Effective between 4.5 and 7.5; ideal for most skin-care and hair-care systems.
Compatibility: Avoid high levels of anionic surfactants that may neutralize cationic activity; nonionic or amphoteric systems perform best.
Synergy: Combine with chelating agents like EDTA and glycols to enhance distribution and efficacy.
Our R&D team assists clients with formulation trials, microbial challenge testing, and stability assessments to guarantee regulatory compliance and commercial success.
Why Source from a China Hexamidine Diisethionate Manufacturer
China has become a strategic hub for cosmetic ingredient manufacturing thanks to advanced chemical synthesis capabilities, cost-effective logistics, and strict quality systems. As a China hexamidine diisethionate manufacturer, CHEN LANG BIO TECH stands out by maintaining pharmaceutical-level facilities equipped with automated crystallization, purification, and drying systems.
We provide:
Consistent Batch Quality: All products undergo multi-stage QC testing for purity, particle size, and moisture.
Full Documentation: TDS, COA, SDS, and REACH support are available for global registration.
Flexible Packaging: Bulk cosmetics powder is supplied in fiber drums or HDPE bags to suit your production scale.
Global Export Network: We ship to Europe, North America, South America, the Middle East, and Asia through trusted logistics partners.
Technical Expertise: Our chemists and formulation engineers provide hands-on support for your development projects.
For international buyers, partnering with a direct producer ensures stable pricing, uninterrupted supply, and faster technical communication compared to trading intermediaries.
Hexamidine Diisethionate Product Information
|
INCI |
Hexamidine diisethionate Powder |
|
Other name |
2-Hydroxyethanesulphonic acid, compound with 4,4'-[hexane-1,6-diylbis(oxy)]bis[benzenecarboxamidine] |
|
EINECS |
211-533-5 |
|
Purity |
99% |
|
CAS |
659-40-5 |
|
Molecular Formula |
C24 H38 N4 O10 S2 |
|
Molecular Weight |
606.72 |
|
Solubility |
soluble in water (80℃) and propylene glycol (60℃), soluble in ethanol, but not in oils. |
|
Functions |
Cosmetics raw materials, preservative |
|
Package |
25Kg/Paper drum |
Quality Assurance and Global Compliance

Our manufacturing process adheres to ISO 9001 and GMP guidelines, with traceability from raw materials to final packaging. Every shipment of bulk hexamidine diisethionate includes analytical COA data verifying identity, purity, and microbiological status.
Compliance is aligned with:
EU Cosmetic Regulation (EC) No 1223/2009;
US FDA VCRP Guidelines;
China NMPA Standards;
SCCS and CIR Safety Assessments.
This documentation ensures seamless product registration and import clearance for global clients.
Certificates of Analysis of Our Hexamidine Diisethionate
CHEN LANG BIO TECH: Your Trusted Hexamidine Diisethionate Partner
As both manufacturer and exporter, CHEN LANG BIO TECH positions itself not just as a supplier but as a long-term technical ally. Our clients range from independent laboratories to multinational beauty corporations. Each partnership benefits from our commitment to quality, confidentiality, and rapid response.
We understand the commercial importance of stable sourcing. With a well-established production capacity and efficient supply chain, we guarantee timely delivery for every order of bulk hexamidine diisethionate—no matter where your facility is located.
Conclusion
Hexamidine diisethionate represents the next generation of cosmetic preservation—scientifically proven, regulatory-compliant, and globally available. For formulators seeking a multifunctional antimicrobial that ensures both product integrity and consumer safety, there is no better choice.
At CHEN LANG BIO TECH, we combine advanced manufacturing technology with decades of formulation expertise to deliver high-purity bulk hexamidine diisethionate to customers worldwide. From hexamidine diisethionate shampoo to facial creams, serums, and deodorants, our ingredient performs consistently across diverse applications.
👉 Contact CHEN LANG BIO TECH today to request a quotation, technical data sheet, or formulation support.
📧 Email: admin@chenlangbio.com
🌐 Website: www.chenlangbio.com
Partner with a China hexamidine diisethionate manufacturer trusted by global brands—and secure a reliable, sustainable source for your next generation of cosmetic innovations.












