Hydroxyethylpiperazine Ethane Sulfonic Acid

Hydroxyethylpiperazine ethane sulfonic acid (HEPES) is a zwitterionic buffering compound frequently used in biological and biochemical research. It is primarily utilized to maintain the pH stability of cell culture media, protein solutions, and various biological buffers.

HEPES is a derivative of piperazine, a cyclic organic compound. It contains a piperazine ring with two ethyl groups and a hydroxyethyl group attached to it, along with a sulfonic acid group (-SO3H) at the end of the molecule. The sulfonic acid group confers water solubility and makes it a good buffer at physiological pH levels.

One of the main reasons for using HEPES as a buffer is its pKa value, which is around 7.5 at room temperature. This means that HEPES can effectively maintain a stable pH in the physiological range, making it suitable for many biological applications. It is widely used in cell culture, enzyme assays, electrophoresis, and molecular biology techniques.

It widely used in cosmetics products.

Principle of Exfoliation:

Human skin is divided into epidermis, dermis and subcutaneous tissue. The epidermis is formed from the outer

Inwardly, it can be divided into stratum corneum, transparent layer, granular layer, spinous layer, and basal layer. Exfoliation refers to the removal of the outermost layer of the skin - the stratum corneum in the epidermis old dead horny.

When the skin's metabolism is not working well, the stratum corneum cannot be shed normally, and the so-called old dead skin cells are formed. When these old dead skin cells accumulate for a long time, it is easy to clog the pores and prevent skin care products from being absorbed.

Hydroxyethylpiperazine ethane sulfonic acid has the effect of loosening cuticles, which can assist in removing aged cuticles on the skin surface, and after hydroxyethylpiperazineethanesulfonic acid softens or removes the stratum corneum, other active ingredients can easily penetrate into skin.

Hydroxyethylpiperazine Ethane Sulfonic Acid in Skin Care:

●Regulate Skin pH:

It can maintain a relatively stable weak acidity range for a long time, and the skin is also weakly acidic. After application of HEPES, it can help adjust the pH of the skin and reduce the pH of the skin surface. It maintains a better fit to help improve skin condition.

●Sunscreen and Whitening:

Hydroxyethylpiperazine ethane sulfonic acid can absorb ultraviolet rays, reduce the stimulation of ultraviolet rays on pigment cells, thereby reducing the formation of melanin in the skin, and has a certain sunscreen and whitening effect.

It can facilitate absorption of active ingredients.

Applications:

Hydroxyethylpiperazine ethane sulfonic acid is a common cosmetic additive, non-toxic, mild, non-irritating, and can assist other ingredients to absorb. Therefore, it is often used in essence, cream, and toner.

Advice Dosage:

0.2-3%.

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